IV Treatment of Migraines

Published : 11/23/2015 19:46:05
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Migraines are headaches that result from a biochemical and neurological imbalance and affect a dominant side of the head. Migraines headaches are usually accompanied by other symptoms such as vision changes (aura), changes in sensitivity to light and sound, nausea and vomiting, and are exacerbated by body movements.

For women, migraines are often the result of hormonal imbalances caused by the use of oral contraceptives or hormone replacement therapy, or menopause. Other possible triggers of migraine attacks are lack of sleep, insomnia, stress, tensional states, magnesium depletion or trauma affecting neurological function.

The treatment of migraines is based on the elimination of triggering factors, reduce muscle tension, improve posture and the supply of nutrients to reduce the frequency and intensity.

In the case that migraine not cease with conventional treatment, doctors resort to intravenous therapy, that is, IV treatment of migraines. This can be done without problems in an outpatient clinic.

Intravenous nutrition

This procedure involves the administration of nutrients directly into the bloodstream. It is a very effective method since the chances of loss of effectiveness is reduced as it passes through the gastrointestinal tract. Intravenous treatment of migraines with vitamins, minerals or certain amino acids is more effective than taking supplements orally. This method allows to correct intracellular deficiencies more quickly, because the nutrients are dumped directly into the place where they are needed. This allows even people with malabsorption disorder can benefit from taking these nutrients, since the digestive system is not used.

Intravenous nutritional therapy is used to increase life energy, repair enzyme systems and promote optimal nerve function. The typical formula for the intravenous treatment of migraine consists of magnesium chloride hexahydrate, calcium gluconate, hydroxocobalamin, pyridoxine hydrochloride, dexpanthenol, B complex 100, Vitamin C, sterile water.

Magnesium: There is scientific evidence that magnesium plays an important role in the pathogenesis of migraine states. IV magnesium is useful as a treatment and as prevention of crises. This mineral acts to reduce inflammation at the level of the nerves and reducing blood vessel spasms, ie constriction. This mineral is a great vasodilator, which is critical when looking to treat migraines.

Magnesium may also suppress the production of serotonin and therefore reduce nausea and vomiting. Intravenous administration of magnesium also works by reducing pain, depression and anxiety.

Riboflavin (B2): It is administered in order to prevent the development of other attacks.

Niacin:  It is used in some patients, especially those with a vascular component, as in larger doses, stimulates blood flow to the periphery and helps in reducing pain.

B vitamins: Vitamin B6 or pyridoxine can reduce homocysteine, which is key to the development of inflammation and cell injury. Vitamin B12 is also important in nerve transmission and the health of the nervous system in general. Low levels of vitamin B12 can also lead to increased serum concentrations of homocysteine, which is counterproductive.

Glutathione: Patients who suffer from migraines often have low levels of glutathione, an enzyme complex with detoxifying  capacity. The administration of glutathione favors the removal of harmful molecules that can cause sensitivity and trigger migraine attacks.


Krusz, John Claude, PhD, MD; Belanger, Jeanne, RN; Cagle, Jane, LVN. “IV Treatment of Refractory Migraines in the Headache Clinic: High Success Rate.”  Poster Abstract. 49th Annual Scientific Meeting of the American Headache Society. Chicago. June, 2007; in Headache, 47:752, May 2007.

Center for the Natural and Integrative Medicine. Intravenous Nutrition.

David Buscher, MD. Intravenous Nutrition.

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