IV Vitamin C for Cancer Treatment

Published : 02/19/2016 20:45:28
Categories : Treatments , Vitamin C

IV Vitamin C has been widely used in complementary medicine to treat cancer patients with good results and now a new study published in Science corroborates this hypothesis.

Since the 1970s, ascorbic acid has been used as adjunctive therapy for the treatment of cancer, mainly supported by its few side effects. In addition, it was used in routine clinical oncology practice but it was abandoned due to multiple clinical trials showed it as ineffective. However, in all cases, it was administered orally.

In 2006, Dr. Padayatty presented three cases of terminal cancer patients given up by Western medicine who recovered and survived after intensive treatment with vitamin C intravenously.

The doses used in natural medicine vary from 7.5 to 30 g per day to 100 g, and this for weeks or months, depending on the evolution of cancer. These megadoses of vitamin C have been shown to have fewer side effects and have contraindications listed below.

It appears that its mechanism of action is the formation of hydrogen peroxide (oxygenated water) in the interstitial tumor tissue, which can destroy many tumor cells, but the peroxide is not formed in the blood and thus, side effects are avoided in the rest of the body. Another possible mechanism of action is the immune modulation of tumor cells, leading thereof, to apoptosis (suicide). Tumors  which development has shown decrease include prostate, pancreatic, colon, leukemia, melanoma, and breast cancer among others.

Oral supplements have not demonstrated improved survival in cancer patients nor be useful for the prevention of this disease.

When vitamin C is administered intravenously, the blood concentrations acquire ten times higher than orally, and at these doses is when vitamin C exerts its anticancer effect. We would have to take enormous amounts of food or supplements to achieve the effective dose.

The intake between 75 and 100 mg of vitamin C a day is recommended to prevent cancer but is not useful to treat it. That is, to prevent it, we would have to take two oranges a day, or a guava, or raw red pepper, a handful of strawberries, two kiwis, or papaya. But this dose would not be adequate for anti-tumoral purposes.

Extremely rare complications of IV Vitamin C for cancer treatment

  • Sudden pain in the areas of tumor deposit.
  • Tumoral hemorrhage (internal or external).
  • Swelling.
  • Severe hypertension.
  • Tachycardia.
  • Azotemia.

Precautions when IV Vitamin C for cancer treatment is used

  • The days when the intravenous infusion is not received, the patient has to take 3-5 grams a day of vitamin C orally to maintain baseline tissue levels and to prevent a crisis from scurvy, a possible rebound effect, very rare, but possible.
  • If the dissolution of Vitamin C becomes too fast or NaCl 0.9% is used as a carrier for dissolution, it can cause local pain and burning sensation in the area.
  • Because ascorbic acid can act as chelating agent, some patients may experience tremors and hypocalcemia.
  • Complications due to increased blood volume: congestive heart failure, ascites, edema, hypertension.


  • Patients on chronic hemodialysis.
  • Unusual forms of iron uptake disorders: hemophilia, major thalassemia.
  • Deficit of Glucose-6-phosphate dehydrogenase (G6PD). It may occur hemolysis and disseminated intravascular coagulation.
  • Renal impairment due to the risk of calcium oxalate deposits. This is a relative contraindication. Renal excretion of calcium oxalate is lower in cancer patients compared to healthy.
  • Very advanced metastatic tumors, avoid high doses of entry due to the risk of bleeding tumor.

To get started with your treatment, just call Dr. Jean Garant on +34 952 770 714, or Email him today to book your consultation.


H.D Riordan et al. Intravenous ascorbic acid: Protocol for ITS application and use. Vol.22 PRHSJ n3, september 2003.

Park S et al. L-ascorbic acid Induc apoptosis in acute myeloid leukemia cells via hydrogen peroxide-mediate Mechanisms. The International Journal of Biochemistry and Cell Biology. 36 (2004), 2180-2195.

  1. Stephenson et al. Phase I Clinical Trial to Evaluate the safety, tolerability and pharmacokinetics of hight-dose intravenous ascorbic acid in Patients with Advanced Cancer. Cancer Chemother Pharmacol (2013) 72: 139-146.

Padayatty S. et al. Vitamin C: intravenous use by alterbative and complementary medicine practitioners and Adverse effects. PLoS ONE 5 (seventh): e11414.doi: 10.1371 / journal.pone. 0011414.

  1. Du et al. Ascorbic acid: chemistry, biology and the treatment of cancer. Biochem Biophys Acta 2012 December.; 1826 (2): 443-457. Doi: 10.1016 / j.bbcan.2012.06.003.

Duconge J. et al. Pharmacokinetics of vitamin C: insights into the oral and intravenous administration of ascorbate. PRHSJ Vol.27 No.1. March, 2008.

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